Live Chat I-26 Community Nearby Traffic US 421 VA 2024-06-05 Roadnow Weather | Gas | Restaurants | Hotels | Car Repair | Convenience Stores Cities close to US 421 VA Nickelsville, VA 9.22 Weber City, VA 13.33 Gate City, VA 14.44 Interstate highway exits close to US 421 VA Exit 66, i81 14.33 Exit 69, i81 15.08 Exit 63, i81 16.83 Interstate highways close to US 421 VA i81 map 14.33 i26 map 24.32 i40 map 105.37 State roads close to US 421 VA US 421 VA map 3.24 VA 71 map 5.93 VA 224 map 10.54