State Route 60 is an 11-mile (18 km) long route in Hale County in the west-central part of the state. The western terminus of the route is at its junction with State Route 14 at Wedgeworth. The eastern terminus of the route is at a junction with State Route 69 at Havana.

State Route 60 passes through rural areas of Alabama’s Black Belt. The route leads northeastwardly from its junction with State Route 14, not passing through any incorporated communities. The route is aligned along a two-lane road from its origin to its terminus.

The entire route is in Hale County.