State Route 37 (SR 37) is a state highway that runs west-to-east through portions of Clay, Calhoun, Baker, Mitchell, Colquitt, Cook, Berrien, Lanier, and Clinch counties in southwestern and south-central Georgia. The route runs from its western terminus at the Alabama state line west of Fort Gaines to its eastern terminus at US 84 and SR 38 west of Homerville.

From its western terminus at the Alabama state line, the route travels east, through Fort Gaines, and through generally rural areas of Clay County and Calhoun County. In the county seat of Calhoun County, Morgan, the route takes a turn to the southeast, passing through Baker County, and its seat, Newton, before entering Mitchell County. In Camilla, the route resumes its easterly routing, passing through the cities of Moultrie and Adel, where it has an interchange with I-75 (unsigned SR 401. In Ray City, SR 37 becomes concurrent with US 129/SR 11 to Lakeland, where US 221/SR 31 join the concurrency. Just east of Lakeland, the routes split, with US 129/SR 11 continuing south and US 221/SR 31 continuing north. SR 37 continues east into Clinch County, where it meets its eastern terminus at US 84/SR 38 west of Homerville.

SR 37 is largely a remote, rural route, with an Average Annual Daily Traffic (AADT) of less than 5,000 vehicles for most of its length, except around Adel and the concurrency with U.S. Routes 129 and 221 east of Lakeland.

State Route 37 Connector (SR 37 CONN) in Camilla, is a short road in the city of Camilla with SR 112 near the Courthouse.

State Route 37 Connector (SR 37 CONN) in Lakeland, is a short road connecting the SR 37 mainline with US 129 just east of Lakeland.