Mississippi Highway 15 (MS 15) is a state highway in Mississippi. At over 328 miles (528 km), it is the longest highway in the Mississippi Highway System. It begins at a junction with U.S. Route 90 in Biloxi and runs northward to the Mississippi/Tennessee state line near Walnut. It serves a total of 15 counties (Harrison, Stone, Perry, Jones, Jasper, Newton, Neshoba, Winston, Choctaw, Webster, Oktibbeha, Chickasaw, Pontotoc, Union, and Tippah). MS 15 is divided into two sections due to a large gap between Stone County and Perry County. The southern section ends at a junction with MS 26, and the northern section begins at a junction with US 98 in Perry County.

From South to North