NC 67 is a 58-mile (93 km) east–west North Carolina state highway. It serves mostly the northern area of Yadkin County, connecting the towns of Jonesville, Boonville and East Bend, along with the city of Winston-Salem in Forsyth County.

The western terminus is Business US 21 in Jonesville. From this point in Yadkin County, the route travels in an easterly direction over Interstate 77, through Boonville and East Bend before crossing the Yadkin River into Forsyth County.

After crossing the county line, NC 67 turns to head in a southeasterly direction through part of Tobaccoville, and near Bethania and Pfafftown on its way into Winston-Salem. Once within Winston-Salem's city limits, the route bears the street name Reynolda Road on its straight southeasterly journey toward downtown. Arriving at the Wake Forest University campus, NC 67 bears right onto a short 0.25-mile (0.40 km) road known as Wake Forest Road, which connects to Silas Creek Parkway, a four-lane boulevard. NC 67 eastbound shares Silas Creek Parkway southbound around Winston-Salem's west side, past Hanes Mall, to end at North Carolina Highway 150 (Peters Creek Parkway) in the city's south side.