State Route 446 (SR 446, OH 446) is an east–west state highway in the northeastern portion of the U.S. state of Ohio. The western terminus of State Route 446 is at a T-intersection with U.S. Route 224 in Canfield, approximately 1 mile (1.6 km) west of the downtown area. Its eastern terminus is at a Y-intersection with State Route 46 about 1 mile (1.6 km) south of Canfield.

Created in the middle of the 1980s, State Route 446, which runs entirely within Mahoning County, is a two-lane highway that bypasses Canfield to the southwest. It connects U.S. Route 224 with State Route 46, and intersects U.S. Route 62 in the process.

State Route 446 is situated entirely within Mahoning County. The route is not included as a part of the National Highway System, a network of highways that are determined to be most important for the country's economy, mobility and defense.

State Route 446 begins at a T-intersection with U.S. Route 224 in the western end of Canfield. The highway starts out heading south, and promptly departs Canfield and enters into the township of the same name. Abutted by forested lands with a few commercial businesses scattered along the way, State Route 446 bends to the southeast, and arrives at its junction with U.S. Route 62, a signalized intersection. Continuing southeast, the route passes a house, then meets the Mill Creek Metroparks Bikeway. Further southeast, it passes more commercial buildings, and is then bounded by farmland on the south side affiliated with Mill Creek Metroparks. State Route 446 reaches its endpoint at this point at a Y-intersection with State Route 46 just south of the city limits of Canfield.

What is now designated as State Route 446 was originally a part of State Route 14, which at the time used this stretch of highway to connect concurrencies it had with U.S. Route 224 and State Route 46, respectively. What is now State Route 14 between Deerfield and Columbiana via Salem was then known as Alternate State Route 14. In 1983, State Route 14's routing was changed to replace what was Alternate State Route 14. U.S. Route 224 and State Route 46 became solo routes in the stretches where they had previously been duplexed with State Route 14, and the former segment of State Route 14 bypassing Canfield to the southwest was given a new highway designation: State Route 446.

The entire route is in Mahoning County.