Pennsylvania Route 315 (PA 315) is an 9-mile (14 km) long state highway located in Luzerne County in Pennsylvania. The southern terminus is at PA 309 in Wilkes-Barre. The northern terminus is at I-81 at Wilkes-Barre/Scranton International Airport in Avoca.

PA 315 begins at an interchange with the PA 309 freeway on the border of Wilkes-Barre and Plains Township, heading northeast on a four-lane divided highway. Southwest of PA 309, the road becomes PA 309 Business. PA 315 becomes a five-lane road with a center left-turn lane as it passes businesses in Plains Township. The road runs a short distance to the west of I-81 and passes Mohegan Sun at Pocono Downs. From this point, the route heads into a mix of woods and commercial development, turning into a three-lane road with one northbound lane and two southbound lanes, running immediately to the west of I-81. Farther northeast, PA 315 becomes a four-lane road and enters more forested areas, briefly crossing into Jenkins Township before entering Laflin. The road passes scattered areas of businesses in this area with one northbound lane and two southbound lanes before passing over a Reading Blue Mountain and Northern Railroad line and crossing back into Jenkins Township. At this point, PA 315 becomes four lanes again and passes through woodland. The road becomes a divided highway again as it comes to an interchange with partial interchange with I-81 that has access to and from the southbound direction of that road.

The route crosses to the east side of I-81 and continues into Pittston Township, where it passes businesses as it reaches a trumpet interchange that connects to the Northeast Extension of the Pennsylvania Turnpike (I-476). A short distance later, PA 315 comes to another interchange with I-81 that has access to and from the northbound direction of the interstate. After this interchange, the route splits into a one-way pair and enters Dupont, with northbound PA 315 following Chestnut Street and southbound PA 315 following Ziegler Street. In this area, the road passes a mix of homes and businesses. In the center of Dupont, southbound PA 315 becomes Main Street, with the two directions of the route joining farther to the north. At this point, the route becomes four-lane undivided Airport Road and enters woodland, crossing into Avoca and turning to the northeast and becoming a divided highway. PA 315 reaches its northern terminus at an interchange with I-81 on the border of Avoca and Pittston Township, with the road continuing to the Wilkes-Barre/Scranton International Airport.

The entire route is in Luzerne County.