Major Cities along US 221 (SC) 2024-05-17 Roadnow US 221 (SC) Major Cities MAP Appling MAP Parksville MAP Plum Branch MAP Modoc MAP Clarks Hill MAP McCormick MAP Ninety Six MAP Bradley MAP Troy MAP Greenwood MAP Waterloo MAP Mountville MAP Laurens MAP Enoree MAP Gray Court MAP Woodruff MAP Moore MAP Roebuck MAP Spartanburg MAP Drayton MAP Chesnee MAP Converse MAP Mayo MAP Cowpens MAP Clinton MAP Harris
