State Highway 352 or SH 352 is a Texas state highway running from Dallas east through Mesquite before finally ending in Sunnyvale. The route mainly runs along Scyene Rd. The highway was designated in 1943 from U.S. Highway 80 in Mesquite west to U.S. Highway 175 southeast of Dallas, and was extended into Dallas in 1964 when US 175 was relocated to the west.

Part of State Highway 352 runs in front of the State Fair of Texas, over a stretch named Robert B. Cullum Boulevard.

SH 352 begins at a junction with I-30 in Dallas and it heads east from this junction through Dallas to an intersection with Loop 12. The highway continues to the east to an intersection within I-635 in Mesquite. SH 352 reaches its eastern terminus at US 80 in Sunnyvale.

The entire route is in Dallas County.