Virginia State Route 105 (SR 105) is a primary state highway in the U.S. state of Virginia. Known as Fort Eustis Boulevard, the state highway runs 4.90 miles (7.89 km) from Fort Eustis in Newport News east to U.S. Route 17 (US 17) near Grafton in York County. SR 105 is a cross-peninsula highway that connects Fort Eustis, a U.S. Army installation, with US 60 and Interstate 64 (I-64), and US 17 near Yorktown.

SR 105 begins at the entrance to Fort Eustis, which is the home of U.S. Army Transportation Corps and the U.S. Army Transportation Museum. The highway continues southwest onto the military base as Washington Boulevard. Just west of SR 105's western terminus, the westbound direction has an at-grade intersection with the Fort Eustis Military Railroad. SR 105 heads east as a four-lane divided highway that has a partial cloverleaf interchange with US 60 (Warwick Boulevard); the interchange includes a flyover ramp from westbound US 60 to westbound SR 105. The state highway crosses Lee Hall Reservoir and CSX's Peninsula Subdivision. East of the railroad, SR 105 has a cloverleaf interchange with I-64 and an intersection with SR 143 (Jefferson Avenue). SR 143 is used as an intermediary for the ramps from westbound I-64 to eastbound SR 105 and from westbound SR 105 to westbound I-64. SR 105 continues east as a two-lane road that is presently being expanded to a four-lane divided highway. The state highway passes along the southern edge of Newport News Park before entering York County, where the highway passes through a forested area with scattered residential subdivisions. SR 105 reaches its eastern terminus at US 17 (George Washington Memorial Highway) between Yorktown to the north and Grafton to the south. Fort Eustis Boulevard continues east as SR 1050 to the named highway's present eastern terminus at SR 634 (Old York Hampton Highway).