Wyoming Highway 210 is a Wyoming State Road known as Happy Jack Road that runs from Cheyenne in Laramie County to 10 miles (16 km) east of Laramie at I-80/US 30 (Exit 323) in Albany County.

Wyoming Highway 210 begins its east end at I-25/US 87 (Exit 10) in Cheyenne. At that interchange, WYO 210 intersects Missile Drive (Former WYO 226) at 0.16 miles (0.26 km) which provides access to F. E. Warren Air Force Base. WYO 210 then continues west passing south of the airbase, and intersecting Wyoming Highway 222 (Fort Access Road) at 2.94 miles (4.73 km). The Laramie-Albany County Line is at Milepost 25.82, and the boundary for Medicine Bow National Forest is at Milepost 26.45. Wyoming Highway 210 ends at 37.79 miles (60.82 km) at the I-80/US 30 interchange (Exit 323) near the State of Wyoming Information Center. Wyoming Highway 210 passes through Vedauwoo, an area of rocky outcrops located in south-eastern Wyoming. At Curt Gowdy State Park, there are two visible reservoirs that supply water to Cheyenne. Both reside on the south side of Happy Jack Road, Crystal reservoir is the farthest east while Granite it farthest west and visible from the highway.