Arkansas Highway 118 is a 60.9-mile (98.0 km) long state highway in Eastern Arkansas. It contains no spur or business routes.

Arkansas Highway 118 begins at US 70/US 79 in West Memphis (at Mid-South Community College) and heads north to meet Interstate 40 before hitting US 64 and angling east by Crawfordsville and Earle. Heading north, the route crosses AR 42 west of Heafer. AR 118 continues north to US 63 and AR 322 south of Tyronza. Now heading west, AR 118 meets AR 135, AR 308, and AR 77 before crossing Interstate 55. After I-55, AR meets US 61 in Joiner. The route continues east to Black Cat, the Mississippi River and Tennessee.