Interstate 271 (I-271) is an auxiliary interstate highway in the suburbs of Cleveland and Akron in the U.S. state of Ohio. The highway is officially designated the Outerbelt East Freeway, but rarely referred to by that name.

The highway runs from a junction with I-71 in Medina Township to I-90 in Willoughby Hills, intersecting I-480 (and running jointly with it for a short stretch). The width varies from point to point, but is mostly four to six lanes wide south of I-480 and eight to twelve lanes wide north of I-480; there it is divided into express and local lanes.

The local-express lanes begin at the southern interchange of US-422 and continue northward slightly beyond the end of I-271. The northbound express lanes allow access to all exits (excluding Chagrin Boulevard, Harvard Road, and SR 175, a southbound-only exit). The southbound express lanes bypass all exits and only have one combined exit for Chagrin Boulevard (east US-422), Harvard Road, Richmond Road (SR 175) and US-422 (west) interchange.

I-290 was to have followed the northern end of I-271. I-271 itself was to have followed I-480N and I-480 westward to I-71.

Interstate 271 does not have a direct interchange with Interstate 80 – one of only a few examples of Interstate Highways that cross but do not intersect. Another example is in Chicago where Interstate 57 crosses Interstate 294 but does not intersect with it. The 271/480 section is the only instance of a concurrency of two three-digit Interstate Highways.

For many years, the interchange with State Route 8 was only partially complete. The northbound exit and southbound entrance ramps connected with both directions of State Route 8, but southbound I-271 could only access State Route 8 southbound (though later both directions were accessible), and only northbound State Route 8 could access I-271 northbound. To compensate for the missing movements, a half-diamond was built at State Route 82. The I-271/State Route 8 interchange underwent reconstruction in 2008–2009 that turned it into a complete interchange allowing all movements.

Similarly, travelers going to and from the north on I-271 had to take surface streets to get to and from the west on I-480 in Cuyahoga County.[citation needed] This link is now covered by unsigned I-480N.