OH 281 Travel Info
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State Route 281 (SR 281) is an east–west state highway in the northwestern portion of the U.S. state of Ohio. Its western terminus is at U.S. Route 24 approximately 4 miles (6.4 km) northeast of Defiance, and its eastern terminus is at U.S. Route 6 nearly 1½ miles north of Bradner. The majority of the route is known as the Defiance Pike.
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