MO 221 Travel Info
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Route 221 is a proposed four-lane road running from Farmington in Saint Francois County to Pilot Knob in Iron County. The route is currently being studied in the Missouri State Transportation Improvement Plan for 2007-2011.
The new route will travel from Farmington to Pilot Knob along Routes V and W. The upgraded road will serve Ironton and Iron County to Saint ... more
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MO 221 Community